entrance at Prenuvo's NYC location
credit: Prenuvo
Prenuvo’s Enhanced Screening combines a full-body MRI with comprehensive bloodwork to create a complete picture of internal health. ATN put it to the test in New York City

Prenuvo, the company best known for bringing full-body MRI scans into mainstream wellness, has expanded its offering with the launch of its Enhanced Screening.

The $4,500 experience combines whole-body imaging with advanced blood testing to deliver a comprehensive view of personal health. I visited Prenuvo’s New York City clinic to see how this new format works in practice and how it fits into the growing world of proactive wellness.

Prenuvo Enhanced Screening Review: How It Works

The process begins several days before the MRI itself. A licensed phlebotomist visited my apartment early in the morning for the blood draw, which is part of Prenuvo’s new protocol. I had to fast the night before and drink plenty of water to make the process smoother. The test evaluates a wide range of biomarkers, including metabolic, cardiovascular, hormonal and immune health indicators. Once processed, these results are integrated directly into the Prenuvo system and later interpreted alongside the imaging data.

When I arrived at the New York City clinic, the experience was streamlined and professional. After checking in, I changed into scrubs in a private suite and was guided into the MRI room for the one-hour scan. It wasn’t particularly comfortable, but it was much better than a typical MRI thanks to Prenuvo’s use of a wider-bore Siemens scanner and the option to watch a movie during the session. The film helped distract from the steady hum and clatter of the machine, which remains an unavoidable part of the process.

MRI scanner and results
credit: Prenuvo

The updated Enhanced Screening also includes more detailed brain sequences to measure blood flow and volume, giving a clearer picture of neurological health.

Prenuvo Enhanced Screening Review: What Comes Next

The most distinctive part of the experience came afterward. During my follow-up consultation a month later, my Prenuvo physician spent close to an hour reviewing the results, integrating insights from both the MRI and bloodwork in a way that felt unusually complete. We walked through every section of the scan, including the brain, spine, organs and muscle composition and compared percentile rankings across different metrics. The platform’s visual interface makes it easy to see how your organs and systems perform relative to others your age, but the physician’s interpretation is what gives the data real context.

What stood out most was how interconnected the findings were. We discussed muscle balance and where one side of my body was stronger than the other, as well as subtle changes that might influence posture or performance. My doctor also noted mild fluid accumulation near my lungs, called pleural effusions, which he connected to possible shifts in iron levels or fluid regulation. I had recently started taking iron supplements and hadn’t mentioned it beforehand, yet it showed up clearly on the scan in connection with my bloodwork. It was an unexpected example of how the body leaves visible clues that technology can now detect.

interior of a Prenuvo NYC location
credit: Prenuvo

This integration of imaging and blood analysis is what differentiates the Enhanced Screening from earlier versions of Prenuvo’s service. Instead of providing separate pieces of information, the system links structural, functional and biochemical data to form a unified picture of health. That level of connection is rare in traditional medicine, where blood tests and imaging are often interpreted in isolation and patients are left to connect the dots themselves.

Prenuvo Enhanced Screening Review: Verdict

While the price definitely makes Prenuvo’s Enhanced Screening a premium offering, the model represents where healthcare is headed: toward personalization, data integration and prevention. The scan isn’t meant to replace regular medical exams or age-based screenings, but it bridges a growing gap between wellness tracking and clinical medicine. For anyone serious about early detection, longevity, or simply understanding their body at a deeper level, the experience delivers valuable insight that goes far beyond curiosity. In an era when so much of healthcare feels fragmented or rushed, Prenuvo’s approach feels refreshingly complete.

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